Mette Aagaard Lund, PhD student27. September 2017
Why did you become a scientist?
I found out that I wanted to be a scientist during my bachelor’s. I was struggling a bit finding my ways at university, but during my bachelor project I discovered that I had a real passion for conducting experiments, analyzing data, and explain the biological results. I therefore studied really hard during my Master’s with the intension to find a really good and interesting master’s project and become a PhD student, so I could explore this passion. Furthermore, I would really like to aid in finding new treatment solutions for CNS diseases or answering questions in the field of drug delivery to the brain as I think this is an area where we are seriously lacking experience, knowledge, and treatment methods.
Can you tell us about your career path to date?
I obtained my bachelor’s degree in biotechnology and my bachelor’s project was about antifungal resistance. However, I was more interested in working with human biology within the pharmaceutical industry, so I continued on the Pharmaceutical Design and engineering Master’s program. During my Master’s I followed the course Drug Delivery, which really got me interested in the development of drug delivery systems. I did my Master’s project in Professor Thomas L Andresen’s lab on developing a method to post-insert antibodies into liposomes and investigate the impact of anti-transferrin receptor antibody (OX26) density on uptake in vitro and transcytosis of OX26 liposomes by pulse chase method in a simple in vitro BBB model. Shortly after I obtained the Master’s degree, I started as a PhD student in Professor Thomas L Andresen’s lab. I am currently in the 3 rd year of my PhD, where my work is mainly focused on redox-sensitive liposomes for brain cancer treatment.
What are you working on at the moment?
At the moment I am working on quantification of intracellular cleavage of redox-sensitive liposomes,preparation of liposomes for 2-photon experiments, and preparation of redox-sensitive liposomes for in vivo studies.
What are your research plans for the next five years?
I will finish my PhD in one year and then I hope to continue as a postdoc to keep investigating and developing drug delivery systems for brain diseases. I hope to be able to contribute to new knowledge on how to exploit the biological environment of the blood-brain barrier and diseased cells for drug delivery.
What do you do when you are not working?
I play football two or three times a week and take spinning classes once or twice a week. Apart from that I spend time with my boyfriend, family and friends.
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